An atypical presentation of a severe and massive atheroembolic disease

J Bras Nefrol. 2019 Jan-Mar;41(1):142-144. doi: 10.1590/2175-8239-JBN-2018-0013. Epub 2018 Aug 20.
[Article in English, Portuguese]

Abstract
in English, Portuguese

Atheroembolic renal disease (AERD) is a kidney manifestation of atherosclerosis as a systemic disease. AERD is defined as a renal impairment secondary to embolization of cholesterol crystals with consequent occlusion of renal vascularization. The current case report describes one patient with multiple risk factors but without any inciting event history who presents a very atypical clinical course of a severe and massive atheroembolic disease that developed spontaneously and silently.

A doença renal ateroembólica (DRAE) é uma manifestação renal da aterosclerose enquanto patologia sistêmica. A DRAE é definida como uma disfunção renal secundária à embolização de cristais de colesterol seguida da oclusão da vascularização renal. O presente relato descreve o caso de um paciente com vários fatores de risco, porém sem um evento precipitante, que se apresentou com um curso clínico bastante atípico de doença ateroembólica grave de evolução espontânea e silenciosa.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anti-Inflammatory Agents / therapeutic use
  • Aspirin / therapeutic use
  • Atherosclerosis / complications*
  • Biopsy
  • Clopidogrel / therapeutic use
  • Creatinine / blood
  • Diabetes Mellitus, Type 2 / complications
  • Diabetic Nephropathies / etiology
  • Dyslipidemias / complications*
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use
  • Hypercholesterolemia
  • Hypertension / complications*
  • Hypertriglyceridemia
  • Kidney / pathology
  • Male
  • Microscopy
  • Platelet Aggregation Inhibitors / therapeutic use
  • Prednisolone / therapeutic use
  • Renal Insufficiency / diagnostic imaging*
  • Renal Insufficiency / drug therapy
  • Renal Insufficiency / etiology*
  • Treatment Outcome

Substances

  • Anti-Inflammatory Agents
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Platelet Aggregation Inhibitors
  • Prednisolone
  • Clopidogrel
  • Creatinine
  • Aspirin