Restriction fragment length polymorphism among Israeli Holstein-Friesian dairy bulls

Anim Genet. 1986;17(1):25-38. doi: 10.1111/j.1365-2052.1986.tb03185.x.

Abstract

Israeli Holstein-Friesian dairy bulls were screened for restriction fragment length polymorphisms by hybridizing cloned DNA probes for bovine growth hormone, for chymosin, and for rat muscle beta-actin to restriction endonuclease-digested DNA immobilized on nitrocellulose filters. The population proved to be polymorphic at the growth hormone locus, with evidence consistent with the phenotypes being inherited in allelic fashion. A low level of polymorphism was also observed at one of the beta-actin gene family loci. The chymosin locus was monomorphic with the restriction enzymes utilized. The results illustrate the power of restriction fragment length polymorphism methodology in visualizing genetic variability in dairy cattle populations.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Actins / genetics
  • Animals
  • Base Sequence
  • Cattle / genetics*
  • Chymosin / genetics
  • DNA / analysis*
  • DNA Restriction Enzymes
  • Genes*
  • Growth Hormone / genetics
  • Israel
  • Male
  • Nucleic Acid Hybridization
  • Polymorphism, Genetic*
  • Protein Biosynthesis
  • Rats
  • Repetitive Sequences, Nucleic Acid

Substances

  • Actins
  • Growth Hormone
  • DNA
  • DNA Restriction Enzymes
  • Chymosin