The International Transporter Consortium: Summarizing Advances in the Role of Transporters in Drug Development

Clin Pharmacol Ther. 2018 Nov;104(5):766-771. doi: 10.1002/cpt.1224.

Authors

Kathleen M Giacomini¹, Aleksandra Galetin², Shiew Mei Huang³

Affiliations

¹ Department of Bioengineering and Therapeutic Sciences, Schools of Pharmacy and Medicine, University of California, San Francisco, California, USA.
² Centre for Applied Pharmacokinetic Research, School of Health Sciences, The University of Manchester, Manchester, UK.
³ Office of Clinical Pharmacology, US Food and Drug Administration, Silver Spring, Maryland, USA.

PMID: 30137696
DOI: 10.1002/cpt.1224

No abstract available

Publication types

Congress
Editorial
Introductory Journal Article

MeSH terms

Animals
Computer Simulation
Drug Development / methods*
Drug Interactions
Humans
Membrane Transport Modulators / chemistry
Membrane Transport Modulators / pharmacology*
Membrane Transport Modulators / toxicity
Membrane Transport Proteins / chemistry
Membrane Transport Proteins / drug effects*
Membrane Transport Proteins / genetics
Membrane Transport Proteins / metabolism
Models, Biological
Models, Molecular
Protein Conformation
Risk Assessment
Structure-Activity Relationship

Substances

Membrane Transport Modulators
Membrane Transport Proteins