Visualisation of the unmet treatment need of osteoporotic fracture in Taiwan: A nationwide cohort study

Int J Clin Pract. 2018 Oct;72(10):e13246. doi: 10.1111/ijcp.13246. Epub 2018 Aug 24.

Abstract

Aims: Recent clinical guidelines have suggested that patients experience an osteoporotic fracture should initiate anti-osteoporosis medications (AOMs). However, whether clinical guidelines translate well in "real-world" practices remain questioned. This study aimed to evaluate the "real-world" prescription pattern of AOMs and visualise the unmet treatment needs in different geographical areas in Taiwan.

Methods: Using Taiwan's National Health Insurance Research Database, we identified patients diagnosed with a hip or vertebral fracture between 2009 and 2012. The treatment rate was defined as the proportion of patients receiving AOMs within 1 year after their index fracture. The qualitative geographical information systems approach was adopted to visualise the treatment needs of postfracture patients in different geographical areas.

Results: Our study included 276,492 patients diagnosed with a hip or vertebral fracture between 2009 and 2012. The proportion of patients who received AOMs within 1 year after their index fracture increased with age and differed with fracture types and sex. For patients with hip fractures, the treatment rate ranged from 3.43% to 20.88% for female patients and from 0.69% to 10.04% for male patients in different age groups. For patients with vertebral fractures, the treatment rate ranged from 3.23% to 37.08% for female patients and from 1.85% to 23.05% for male patients. Cities in the mid-northern and southern areas of Taiwan had the highest unmet treatment need, with a treatment rate of less than 15%.

Conclusion: The treatment rate of osteoporotic fractures with AOMs was diverse and suboptimal in Taiwan, especially among male patients. This study used a visualisation technique to display information about the treatment status in different geographical areas and help policymakers allocate resource appropriately.

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Bone Density Conservation Agents / therapeutic use*
  • Databases, Factual
  • Female
  • Geographic Information Systems
  • Health Services Needs and Demand*
  • Hip Fractures / etiology
  • Hip Fractures / prevention & control
  • Humans
  • Male
  • Middle Aged
  • National Health Programs / statistics & numerical data
  • Needs Assessment
  • Osteoporosis / complications
  • Osteoporosis / drug therapy*
  • Osteoporotic Fractures / etiology
  • Osteoporotic Fractures / prevention & control*
  • Retrospective Studies
  • Secondary Prevention / statistics & numerical data*
  • Sex Factors
  • Spatial Analysis
  • Spinal Fractures / etiology
  • Spinal Fractures / prevention & control
  • Taiwan

Substances

  • Bone Density Conservation Agents