Immunization of Solid Organ Transplant Candidates and Recipients: A 2018 Update

Christian Donato-Santana; Nicole M Theodoropoulos

doi:10.1016/j.idc.2018.04.002

Immunization of Solid Organ Transplant Candidates and Recipients: A 2018 Update

Infect Dis Clin North Am. 2018 Sep;32(3):517-533. doi: 10.1016/j.idc.2018.04.002.

Authors

Christian Donato-Santana¹, Nicole M Theodoropoulos²

Affiliations

¹ Division of Infectious Diseases & Immunology, University of Massachusetts Medical School, 55 Lake Avenue North, S7-715, Worcester, MA 01655, USA.
² Division of Infectious Diseases & Immunology, University of Massachusetts Medical School, 55 Lake Avenue North, S7-715, Worcester, MA 01655, USA. Electronic address: [email protected].

PMID: 30146021
DOI: 10.1016/j.idc.2018.04.002

Abstract

This article discusses the recommended vaccines used before and after solid organ transplant period, including data regarding vaccine safety and efficacy and travel-related vaccines. Vaccination is an important part of the preparation for solid organ transplantation, because vaccine-preventable diseases contribute to the morbidity and mortality of these patients. A pretransplantation protocol should be encouraged in every transplant center. The main goal of vaccination is to provide seroprotection before transplantation, because iatrogenically immunosuppressed patients posttransplant have a lower seroresponse to vaccines.

Keywords: Immunization; Immunosuppressed; Solid organ transplant; Vaccine.

Publication types

Review

MeSH terms

Communicable Disease Control*
Humans
Immunization*
Organ Transplantation / adverse effects*
Tissue Donors*
Transplant Recipients*
Vaccines / administration & dosage*

Substances

Vaccines