Harbouring group B streptococci in a neonatal intensive care unit led to an outbreak among preterm infants

Acta Paediatr. 2019 Jan;108(1):58-61. doi: 10.1111/apa.14558. Epub 2018 Sep 21.

Abstract

We report a nosocomial outbreak with group B streptococci (GBS) in a level two neonatal intensive care unit (NICU) at Sachs' Children and Youth Hospital, Stockholm, Sweden, in 2014. There were five very preterm infants with severe late-onset septicaemia, and 10 further infants were colonised. Pulsed-field gel electrophoresis and multilocus sequence typing genetic characterisation showed that one GBS strain was the cause: serotype Ia, sequence type 23, clonal complex 23. The NICU environment cultures revealed GBS reservoirs on surfaces near sick and colonised patients. We identified workflows and guidelines that could increase the risks of nosocomial infections. Conclusion: This nosocomial GBS outbreak among preterm infants demonstrates that GBS can be harboured in the NICU environment.

Keywords: Group B streptococci; Neonatal intensive care unit; Nosocomial outbreak; Preterm infants; Septicaemia.

Publication types

  • Multicenter Study

MeSH terms

  • Bacteremia / diagnosis
  • Bacteremia / epidemiology*
  • Cross Infection / epidemiology*
  • Cross Infection / microbiology
  • Disease Outbreaks / statistics & numerical data*
  • Disease Progression
  • Female
  • Gestational Age
  • Hospital Mortality
  • Humans
  • Infant, Newborn
  • Infant, Premature
  • Intensive Care Units, Neonatal / statistics & numerical data*
  • Pregnancy
  • Retrospective Studies
  • Streptococcal Infections / diagnosis
  • Streptococcal Infections / drug therapy
  • Streptococcal Infections / epidemiology*
  • Streptococcus agalactiae / isolation & purification*
  • Survival Analysis
  • Sweden