Acute onset/flares of dermatomyositis following ingestion of IsaLean herbal supplement: Clinical and immunostimulatory findings

J Am Acad Dermatol. 2019 Mar;80(3):801-804. doi: 10.1016/j.jaad.2018.08.019. Epub 2018 Aug 27.

Authors

Majid Zeidi¹, Peter B Chansky¹, Victoria P Werth²

Affiliations

¹ Department of Dermatology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania; Corporal Michael J. Crescenz Veterans Administration Medical Center, Philadelphia, Pennsylvania.
² Department of Dermatology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania; Corporal Michael J. Crescenz Veterans Administration Medical Center, Philadelphia, Pennsylvania. Electronic address: [email protected].

PMID: 30165168
DOI: 10.1016/j.jaad.2018.08.019

No abstract available

Publication types

Letter

MeSH terms

Acute Disease
Autoantibodies / blood*
Autoimmune Diseases / blood
Autoimmune Diseases / etiology*
Dermatomyositis / blood
Dermatomyositis / etiology*
Dietary Supplements / adverse effects*
Humans
Hydroxychloroquine / pharmacology
Interferon-alpha / metabolism
Interferon-beta / metabolism
Leukocytes, Mononuclear / drug effects
Leukocytes, Mononuclear / metabolism
Lipopolysaccharides / pharmacology
Primary Cell Culture
Quinacrine / pharmacology
Symptom Flare Up
Toll-Like Receptor 4 / antagonists & inhibitors
Tumor Necrosis Factor-alpha / metabolism

Substances

Autoantibodies
Interferon-alpha
Lipopolysaccharides
TLR4 protein, human
Toll-Like Receptor 4
Tumor Necrosis Factor-alpha
Hydroxychloroquine
Interferon-beta
Quinacrine