Superficial Siderosis of the Central Nervous System Due to Recurrent Surgeries of the Thoracic Spine: A Rare Case

World Neurosurg. 2018 Nov:119:384-388. doi: 10.1016/j.wneu.2018.08.140. Epub 2018 Aug 27.

Abstract

Background: Superficial siderosis (SS) of the central nervous system is a rare condition caused by hemosiderin deposition in the subpial layers of the brain and spinal cord. Surgical complications are the primary factor for occurrence of secondary SS. We present a case of SS with an identified bleeding origin in the thoracic spine.

Case description: A 58-year-old female patient experienced 9 months of continuous progressive dizziness, difficulty with mobilization, drop attacks, and lack of hearing. The patient also had an extensive history of thoracic spinal surgeries. She came to the hospital with gait imbalance. Gradient echo (GE) magnetic resonance imaging (MRI) confirmed hemosiderin deposition along the cerebellar folia and vermis. GE sequences are preferable in this diagnosis, because of higher sensitivity, and for detecting characteristic T2 hypointensity. The dural defect was repaired with an artificial dural patch in thoracal operation area. Clinical findings, imaging studies, intraoperative findings, and literature information are presented.

Conclusions: Performance of an open neurosurgical procedure to repair a dural defect in the presence of MRI confirmed that superficial siderosis is an optimal method and a crucial step to ensure the safe resolution of the condition and to break the circle of emergency admissions of a patient with a dural defect and a history of multiple spinal surgeries.

Keywords: Brain; Cerebellum; Dural defect; Spinal surgery; Superficial siderosis.

Publication types

  • Case Reports

MeSH terms

  • Central Nervous System / diagnostic imaging*
  • Female
  • Hemosiderin / metabolism
  • Humans
  • Laminectomy / adverse effects*
  • Magnetic Resonance Imaging
  • Middle Aged
  • Postoperative Complications / diagnostic imaging
  • Postoperative Complications / physiopathology*
  • Siderosis / diagnostic imaging
  • Siderosis / etiology*
  • Spinal Cord / diagnostic imaging
  • Spinal Cord / surgery*
  • Thoracic Vertebrae / diagnostic imaging
  • Thoracic Vertebrae / surgery*

Substances

  • Hemosiderin