A stress associated NAC transcription factor MpSNAC67 from banana (Musa x paradisiaca) is involved in regulation of chlorophyll catabolic pathway

Plant Physiol Biochem. 2018 Nov:132:61-71. doi: 10.1016/j.plaphy.2018.08.020. Epub 2018 Aug 22.

Abstract

Process of senescence includes multiple steps involving break-down of chlorophyll to degrade photosynthetic machinery. In this study, we showed that a stress-associated NAC transcription factor MpSNAC67 regulates senescence by promoting chlorophyll-catabolic genes. MpSNAC67 encodes a transcriptional activator and its promoter activity is restricted to vascular tissue of banana. Expression of MpSNAC67 showed positive responses to multiple abiotic stress conditions suggesting that MpSNAC67 is a stress associated NAC transcription factor. Transgenic banana lines overexpressing MpSNAC67 showed highly senesced phenotype including yellowing and de-greening of leaves similar to etiolated leaves. Transgenic leaves possessed low chlorophyll content and failed to retain normal chloroplast morphology including loss of granum thylakoid, non-uniform chloroplast membrane and increased number as well as size of plastoglobulins. In a gel shift assay MpSNAC67 could retard the mobility of chlorophyll catabolic genes such as PAO-like (Pheophorbide-a-oxygenase), HCAR-like (hydroxymethyl chlorophyll-a-reductase), NYC/NOL-like (Chlorophyll-b-reductase) as well as ORS1-like (a SenNAC). Expression of these genes were highly elevated in transgenic lines which indicate that MpSNAC67 is a positive regulator of senescence in banana and exercise its effect by regulating the expression of chlorophyll catabolic genes and ORS1.

Keywords: Banana; Chlorophyll degradation; Gene expression; Musa; SNAC67; Transgenic.

MeSH terms

  • Base Sequence
  • Chlorophyll / metabolism*
  • Chloroplasts / metabolism
  • Chloroplasts / ultrastructure
  • Crosses, Genetic
  • Droughts
  • Gene Expression Profiling
  • Gene Expression Regulation, Plant
  • Metabolic Networks and Pathways*
  • Musa / genetics
  • Musa / metabolism*
  • Musa / physiology
  • Musa / ultrastructure
  • Organ Specificity / genetics
  • Phenotype
  • Plant Proteins / chemistry
  • Plant Proteins / metabolism
  • Plants, Genetically Modified
  • Promoter Regions, Genetic
  • Protein Binding
  • Protein Domains
  • Salinity
  • Stress, Physiological* / genetics
  • Trans-Activators / metabolism
  • Transcription Factors / chemistry
  • Transcription Factors / genetics
  • Transcription Factors / metabolism*

Substances

  • Plant Proteins
  • Trans-Activators
  • Transcription Factors
  • Chlorophyll