Effect of alternative positions of neonates prior to delayed cord clamping on placental transfusion: a randomized control trial

J Matern Fetal Neonatal Med. 2020 May;33(9):1511-1516. doi: 10.1080/14767058.2018.1520834. Epub 2018 Sep 26.

Abstract

Objective: To determine the effect of alternative positions (relative to placenta) of normal term neonates, prior to the recommended delayed cord clamping, on placental transfusion and short-term neonatal outcome.Methods: Normal term neonates born vaginally were randomly assigned to be placed either on mother's abdomen (Group AL, n = 97) or 20 cm below the introitus (Group BL, n = 102) for 90 seconds after delivery. Subsequently the cord was clamped. Outcome measures were anthropometry, hematological profile including ferritin at birth and at 3-4 months; and adverse effects, polycythemia, and jaundice.Results: Both groups had comparable outcome measures at birth. At 3-4 months, mean hemoglobin (AL: 12.0 ± 0.9 g/dl, BL: 12.3 ± 1.1 g/dl; p = .02, 95% CI: 0.03-0.58) and hematocrit (AL: 36.1 ± 2.7%, BL: 37 ± 3.2%; p = .01, 95% CI: 0.1-1.75) were significantly higher in BL group. Anthropometry, serum ferritin, incidence of anemia and iron deficiency at 3-4 months were similar in both groups. There was no significant difference in polycythemia, jaundice requiring phototherapy or respiratory distress between the two groups.Conclusions: Placing the baby below the placenta resulted in a statistically significant increase in hemoglobin and hematocrit at 3-4 months without any adverse outcomes. However, this meager quantum of increase did not translate into reduction of risk of anemia or improvement in iron stores.

Keywords: Anemia; iron deficiency; placental transfusion; position at birth.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Anemia, Iron-Deficiency / prevention & control
  • Delivery, Obstetric / methods*
  • Female
  • Ferritins / blood
  • Hematocrit
  • Humans
  • India
  • Infant
  • Infant, Newborn
  • Patient Positioning / methods*
  • Placental Circulation / physiology*
  • Pregnancy
  • Umbilical Cord / blood supply*

Substances

  • Ferritins