Abstract
Primary classic Hodgkin lymphoma of the gastrointestinal tract represents a rare occurrence. A full patient's work-up is essential in order to exclude a secondary intestinal involvement. Histologically Epstein-Barr virus mucocutaneous ulcer closely resembles Hodgkin lymphoma. The differential diagnosis between these two entities is relevant, since both the therapeutic approach and the clinical behavior are different. Herein, we describe a case of primary classic Hodgkin lymphoma arising in the ileum and a case of Epstein-Barr virus mucocutaneous ulcer of the colon, focusing on the main clinicopathological differences.
Keywords:
Diverticulitis; Epstein-Barr virus; Hodgkin lymphoma; Mucocutaneous; Ulcer.
Publication types
-
Case Reports
-
Comparative Study
MeSH terms
-
Adult
-
Aged, 80 and over
-
Biomarkers, Tumor / analysis
-
Biopsy
-
Colonic Diseases / immunology
-
Colonic Diseases / pathology*
-
Colonic Diseases / virology
-
Diagnosis, Differential
-
Epstein-Barr Virus Infections / immunology
-
Epstein-Barr Virus Infections / pathology*
-
Epstein-Barr Virus Infections / virology
-
Female
-
Hodgkin Disease / drug therapy
-
Hodgkin Disease / metabolism
-
Hodgkin Disease / pathology*
-
Humans
-
Ileal Neoplasms / chemistry
-
Ileal Neoplasms / drug therapy
-
Ileal Neoplasms / pathology*
-
Immunocompromised Host
-
Immunohistochemistry
-
Immunosuppressive Agents / adverse effects
-
Male
-
Methotrexate / adverse effects
-
Opportunistic Infections / immunology
-
Opportunistic Infections / pathology*
-
Opportunistic Infections / virology
-
Predictive Value of Tests
-
Ulcer / immunology
-
Ulcer / pathology*
-
Ulcer / virology
Substances
-
Biomarkers, Tumor
-
Immunosuppressive Agents
-
Methotrexate