Structural and functional insights into MCR-2 mediated colistin resistance

Sci China Life Sci. 2018 Nov;61(11):1432-1436. doi: 10.1007/s11427-018-9363-4. Epub 2018 Sep 3.
No abstract available

Publication types

  • Letter

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Binding Sites
  • Catalytic Domain
  • Colistin / pharmacology*
  • Drug Resistance, Bacterial / genetics*
  • Escherichia coli / drug effects
  • Escherichia coli / enzymology
  • Escherichia coli / genetics
  • Escherichia coli Proteins / chemistry
  • Escherichia coli Proteins / genetics*
  • Escherichia coli Proteins / metabolism
  • Membrane Proteins / chemistry
  • Membrane Proteins / genetics*
  • Membrane Proteins / metabolism
  • Microbial Sensitivity Tests
  • Models, Molecular
  • Molecular Docking Simulation
  • Mutation
  • Plasmids
  • Structure-Activity Relationship

Substances

  • Anti-Bacterial Agents
  • Escherichia coli Proteins
  • Membrane Proteins
  • mcr-2 protein, E coli
  • Colistin