Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines on the Evaluation and Treatment of Patients With Thoracolumbar Spine Trauma: Pharmacological Treatment

Neurosurgery. 2019 Jan 1;84(1):E36-E38. doi: 10.1093/neuros/nyy371.

Abstract

Question: Does the administration of a specific pharmacologic agent (eg, methylprednisolone) improve clinical outcomes in patients with thoracic and lumbar fractures and spinal cord injury?

Recommendation: There is insufficient evidence to make a recommendation; however, the task force concluded, in light of previously published data and guidelines, that the complication profile should be carefully considered when deciding on the administration of methylprednisolone. Strength of recommendation: Grade Insufficient The full version of the guideline can be reviewed at: https://www.cns.org/guideline-chapters/congress-neurological-surgeons-systematic-review-evidence-based-guidelines/chapter_5.

Publication types

  • Guideline
  • Systematic Review

MeSH terms

  • Evidence-Based Medicine
  • Guidelines as Topic
  • Humans
  • Lumbar Vertebrae / injuries*
  • Methylprednisolone / therapeutic use
  • Neurosurgery / standards*
  • Spinal Fractures / drug therapy
  • Spinal Fractures / surgery
  • Spinal Injuries / drug therapy*
  • Thoracic Vertebrae / injuries*

Substances

  • Methylprednisolone