Atrial fibrillation independently linked with depression in community-dwelling older population. Results from the nationwide PolSenior project

Exp Gerontol. 2018 Oct 2:112:88-91. doi: 10.1016/j.exger.2018.09.006. Epub 2018 Sep 13.

Abstract

Background: Depression is a frequently observed comorbid condition in patients with cardiovascular diseases. In contrast to coronary heart disease and heart failure there is a limited amount of published data concerning the increased prevalence of depression among patients with atrial fibrillation (AF). Therefore, we decided to assess the prevalence of depression in Polish community-dwelling older patients with a history of AF.

Methods: The data were collected as part of the nationwide PolSenior project (2007-2012). Out of 4979 individuals (age range 65-104 years), data on self-reported history of AF were available for 4677 (93.9%). Finally, 4049 participants without suspected moderate or severe dementia in Mini Mental State Examination test were assessed with the 15-item Geriatric Depression Scale (GDS), and a score of 6 points and more was regarded as suspected depression.

Results: Mean age (±SD) of the study population was 78.1 (±8.3) years; 52% were males. The history of AF was reported by 788 (19.5%) subjects. In the univariate analysis a self-reported AF history was associated with 42% increase of suspected depression (41% vs 29%; P < 0.001). In multivariate logistic regression AF remained an independent predictor of depression (OR = 1.69; 95%CI: 1.43-2.00), stronger than heart failure, diabetes or coronary heart disease.

Conclusions: In community-dwelling geriatric Polish population AF is associated with higher prevalence of depression. This association is independent from the demographic factors, disabilities and comorbidities (including history of stroke).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Atrial Fibrillation / epidemiology*
  • Atrial Fibrillation / psychology*
  • Comorbidity
  • Dementia / epidemiology
  • Depression / epidemiology*
  • Diabetes Mellitus / epidemiology
  • Female
  • Geriatric Assessment
  • Heart Failure / epidemiology
  • Humans
  • Logistic Models
  • Male
  • Multivariate Analysis
  • Poland / epidemiology
  • Prevalence
  • Self Report