Two novel HLA-B alleles, HLA-B*53:01:17 and -B*58:83, found in patients from Guinea-Bissau

HLA. 2018 Dec;92(6):417-418. doi: 10.1111/tan.13392. Epub 2018 Oct 29.

Abstract

Novel HLA-B alleles HLA-B*53:01:17 and HLA-B*58:83 are described in two patients from Guinea-Bissau.

Keywords: HIV-2; HLA; HLA-B; next-generation sequencing.

Publication types

  • Case Reports

MeSH terms

  • Alleles*
  • Amino Acid Substitution
  • Base Sequence
  • Codon / chemistry
  • Exons*
  • Gene Expression
  • Genotype
  • Guinea-Bissau
  • HIV Infections / genetics*
  • HIV Infections / immunology
  • HIV Infections / virology
  • HIV-2 / classification
  • HIV-2 / genetics
  • HIV-2 / isolation & purification
  • HLA Antigens / genetics*
  • HLA Antigens / immunology
  • HLA-B Antigens / genetics*
  • HLA-B Antigens / immunology
  • Histocompatibility Testing
  • Host-Pathogen Interactions / genetics
  • Host-Pathogen Interactions / immunology
  • Humans
  • Polymerase Chain Reaction
  • Polymorphism, Single Nucleotide*
  • RNA, Viral / genetics*
  • RNA, Viral / isolation & purification
  • Sequence Alignment
  • Sequence Analysis, DNA

Substances

  • Codon
  • HLA Antigens
  • HLA-B Antigens
  • HLA-B53 antigen
  • HLA-B58 antigen
  • RNA, Viral