Persistence of NS5B-S282T, a sofosbuvir resistance-associated substitution, in a HIV/HCV-coinfected MSM with risk of onward transmission

J Hepatol. 2018 Oct;69(4):968-970. doi: 10.1016/j.jhep.2018.06.021. Epub 2018 Jul 4.
No abstract available

Keywords: Hepatitis C virus; Men who have sex with men; Resistance-associated substitution; S282T; Transmission.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Aged
  • Antiviral Agents / therapeutic use*
  • Coinfection / drug therapy*
  • Coinfection / virology
  • Drug Resistance, Viral
  • HIV Infections / virology*
  • Hepatitis C, Chronic / drug therapy*
  • Hepatitis C, Chronic / transmission
  • Hepatitis C, Chronic / virology
  • Homosexuality, Male*
  • Humans
  • Male
  • Mutation*
  • RNA, Viral / blood
  • Sofosbuvir / therapeutic use*
  • Viral Nonstructural Proteins / genetics*

Substances

  • Antiviral Agents
  • RNA, Viral
  • Viral Nonstructural Proteins
  • NS-5 protein, hepatitis C virus
  • Sofosbuvir