Identifying the Patterns of Pattern Recognition Receptors

Andrea A Hill; Gretchen E Diehl

doi:10.1016/j.immuni.2018.08.027

Identifying the Patterns of Pattern Recognition Receptors

Immunity. 2018 Sep 18;49(3):389-391. doi: 10.1016/j.immuni.2018.08.027.

Authors

Andrea A Hill¹, Gretchen E Diehl²

Affiliations

¹ Alkek Center for Metagenomics and Microbiome Research and the Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA.
² Alkek Center for Metagenomics and Microbiome Research and the Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA; Biology of Inflammation Center, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address: [email protected].

PMID: 30231979
DOI: 10.1016/j.immuni.2018.08.027

Abstract

Intestinal homeostasis requires microbial recognition that results in appropriate responses to commensals and pathogens. In this issue of Immunity, Price et al. (2018) map the in vivo expression of five toll-like receptors (TLR) in intestinal epithelia, revealing distinct spatio-temporal expression patterns that shape responses to TLR ligands.

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MeSH terms

Immunity
Intestinal Mucosa*
Ligands
Toll-Like Receptors*

Substances

Ligands
Toll-Like Receptors