Abstract
Two group A, subgroup I, rotavirus strains possessing "super short" RNA patterns were adapted to growth in MA-104 cells. Both produced marked cytopathic effect in primary culture. Reciprocal cross-neutralization titers, polypeptide analysis, and the serum neutralizing antibody response of an infected child suggested that super short viruses are serotypically distinct from the four recognized human serotypes.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Antibodies, Viral / analysis
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Antigens, Viral / analysis
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Cell Line
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Cytopathogenic Effect, Viral
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Electrophoresis, Polyacrylamide Gel
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Humans
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Infant
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Molecular Weight
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Neutralization Tests
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Peptides / analysis
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RNA, Viral / analysis*
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Rotavirus / classification
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Rotavirus / genetics*
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Rotavirus / physiology
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Serotyping
Substances
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Antibodies, Viral
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Antigens, Viral
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Peptides
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RNA, Viral