Emerging Role of Diet and Microbiota Interactions in Neuroinflammation

Front Immunol. 2018 Sep 11:9:2067. doi: 10.3389/fimmu.2018.02067. eCollection 2018.

Abstract

Commensal gut microbiota exerts multifarious effects on intestinal and extra-intestinal immune homeostasis. A disruption in the microbial composition of the gut has been associated with many neurological disorders with inflammatory components. Here we review known associations between gut microbiota and neurological disorders. Further we highlight the emerging role of diet and microbiota interrelationship in regulating neuroinflammation.

Keywords: EAE; MS; diet; microbiome; neuroinflammation.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Diet*
  • Gastrointestinal Microbiome / immunology*
  • Humans
  • Inflammation / immunology
  • Inflammation / microbiology
  • Inflammation / pathology
  • Nervous System Diseases* / immunology
  • Nervous System Diseases* / microbiology
  • Nervous System Diseases* / pathology