Hypernatraemia in 39 hospitalised foals: clinical findings, primary diagnosis and outcome

Aust Vet J. 2018 Oct;96(10):385-389. doi: 10.1111/avj.12749.

Abstract

Objective: To evaluate hypernatraemia in foals presenting as medical emergencies to an intensive care unit (ICU) to determine the prevalence, clinical findings, primary diagnosis and outcome.

Methods: Retrospective case study of records from Thoroughbred foals aged less than 3 months that presented to an ICU as medical emergencies in 2002-12. Data retrieved included signalment, clinical findings, laboratory results, primary diagnosis and outcome. Foals with hypernatraemia (serum sodium > 145 mmol/L) on admission laboratory data were identified and further evaluated.

Results: A total of 39 of 1718 foals (2.3%) were diagnosed with hypernatraemia; all foals were less than 7 days of age. The most common primary diagnoses in the foals with hypernatraemia were neonatal syndrome (19/39, 48.7%) and sepsis (15/39, 38.5%). Foals with hypernatraemia at presentation were more likely to die or be euthanased during their hospitalisation than foals with a normal serum sodium concentration on ICU admission (33.3% vs 16.1%; odds ratio, 2.3; 95% confidence interval, 1.2-4.6; P = 0.02).

Conclusion: Admission hypernatraemia was an uncommon but important electrolyte abnormality in this population of hospitalised foals. Although the short-term outcome in survivors was most likely dependent on the underlying disease process, hypernatraemia was negatively associated with outcome in hospitalised foals.

Keywords: critical care; electrolytes; foals; hypernatraemia; sodium; water balance.

MeSH terms

  • Animals
  • Animals, Newborn / blood
  • Female
  • Horse Diseases / diagnosis*
  • Horse Diseases / mortality
  • Horse Diseases / therapy
  • Horses
  • Hypernatremia / diagnosis
  • Hypernatremia / mortality
  • Hypernatremia / therapy
  • Hypernatremia / veterinary*
  • Male
  • Prevalence
  • Retrospective Studies
  • Sepsis / veterinary
  • Sodium / blood
  • Treatment Outcome

Substances

  • Sodium