Usefulness of indocyanine green-fluorescence imaging for real-time visualization of pancreas neuroendocrine tumor and cystic neoplasm

Chikara Shirata; Yoshikuni Kawaguchi; Kosuke Kobayashi; Yuta Kobayashi; Junichi Arita; Nobuhisa Akamatsu; Junichi Kaneko; Yoshihiro Sakamoto; Norihiro Kokudo; Kiyoshi Hasegawa

doi:10.1002/jso.25231

Usefulness of indocyanine green-fluorescence imaging for real-time visualization of pancreas neuroendocrine tumor and cystic neoplasm

J Surg Oncol. 2018 Nov;118(6):1012-1020. doi: 10.1002/jso.25231. Epub 2018 Sep 27.

Affiliation

¹ Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

PMID: 30261107
DOI: 10.1002/jso.25231

Abstract

We evaluated the usefulness of fluorescence imaging using indocyanine green to identify pancreas tumors in 23 patients undergoing pancreas resection. This technique was useful in visualizing pancreas lesions during surgery, specifically, neuroendocrine tumors as fluorescence and cystic neoplasms as a fluorescence defect.

Keywords: fluorescence imaging (FI); indocyanine green (ICG); neuroendocrine tumor (NET); pancreas cystic neoplasm; pancreas lesion; pancreas resection.

MeSH terms

Adult
Aged
Aged, 80 and over
Carcinoma, Pancreatic Ductal / blood supply
Carcinoma, Pancreatic Ductal / diagnostic imaging
Carcinoma, Pancreatic Ductal / pathology
Carcinoma, Pancreatic Ductal / surgery
Coloring Agents
Female
Humans
Indocyanine Green*
Male
Middle Aged
Neuroendocrine Tumors / blood supply
Neuroendocrine Tumors / diagnostic imaging*
Neuroendocrine Tumors / pathology
Neuroendocrine Tumors / surgery*
Optical Imaging / methods*
Pancreatic Cyst / blood supply
Pancreatic Cyst / diagnostic imaging*
Pancreatic Cyst / pathology
Pancreatic Cyst / surgery*
Pancreatic Neoplasms / blood supply
Pancreatic Neoplasms / diagnostic imaging*
Pancreatic Neoplasms / pathology
Pancreatic Neoplasms / surgery*
Young Adult

Substances

Coloring Agents
Indocyanine Green