Calcipotriene plus betamethasone dipropionate in aerosol foam formulation: will this effective treatment for mild-to-moderate psoriasis change clinical practice?

G Ital Dermatol Venereol. 2018 Dec;153(6):872-876. doi: 10.23736/S0392-0488.18.06143-6. Epub 2018 Sep 27.

Abstract

The fixed-combination of Cal/BD aerosol foam is now entering the Italian market. This drug was developed with a technology that allows an enhanced penetration of the active ingredients into the skin. This enhanced penetration improves local bioavailability and, consequently, Cal/BD aerosol foam therapy is associated with improved clinical outcomes if compared with other products with the same components. The efficacy and safety of Cal/BD aerosol foam were confirmed both in clinical trials and in "field-practice" studies. This short review discusses current evidence on the Cal/BD aerosol foam combination; some preliminary data collected in the Italian clinical practice will be also presented.

Publication types

  • Review

MeSH terms

  • Administration, Cutaneous
  • Aerosols
  • Betamethasone / administration & dosage
  • Betamethasone / adverse effects
  • Betamethasone / analogs & derivatives*
  • Betamethasone / pharmacokinetics
  • Biological Availability
  • Calcitriol / administration & dosage
  • Calcitriol / adverse effects
  • Calcitriol / analogs & derivatives*
  • Calcitriol / pharmacokinetics
  • Dermatologic Agents / administration & dosage*
  • Dermatologic Agents / adverse effects
  • Dermatologic Agents / pharmacokinetics
  • Drug Combinations
  • Humans
  • Italy
  • Psoriasis / drug therapy*
  • Psoriasis / pathology
  • Skin Absorption
  • Treatment Outcome

Substances

  • Aerosols
  • Dermatologic Agents
  • Drug Combinations
  • betamethasone dipropionate, calcipotriol drug combination
  • Betamethasone
  • Calcitriol