Development and validation of a simple tool for the assessment of home noninvasive ventilation: the S3-NIV questionnaire

Elise Dupuis-Lozeron; Grégoire Gex; Patrick Pasquina; Pierre-Olivier Bridevaux; Jean-Christian Borel; Paola M Soccal; Wolfram Windisch; Jean-Louis Pépin; Jean-Paul Janssens; Dan Adler

doi:10.1183/13993003.011822018

Development and validation of a simple tool for the assessment of home noninvasive ventilation: the S³-NIV questionnaire

Eur Respir J. 2018 Nov 22;52(5):1801182. doi: 10.1183/13993003.011822018. Print 2018 Nov.

Authors

Elise Dupuis-Lozeron¹, Grégoire Gex^{2

3}, Patrick Pasquina³, Pierre-Olivier Bridevaux^{2

3

4}, Jean-Christian Borel⁵, Paola M Soccal^{3

4}, Wolfram Windisch^{6

7}, Jean-Louis Pépin^{8

9}, Jean-Paul Janssens^{3

4}, Dan Adler^{3

4}

Affiliations

¹ Division of Clinical Epidemiology, Geneva University Hospitals, Geneva, Switzerland.
² Division of Lung Diseases, Hôpital du Valais, Sion, Switzerland.
³ Division of Lung Diseases, Geneva University Hospitals, Geneva, Switzerland.
⁴ University of Geneva Medical School, Geneva, Switzerland.
⁵ AGIR à dom, Grenoble, France.
⁶ Cologne Merheim Hospital, Dept of Pneumology, Kliniken der Stadt Köln, Cologne, Germany.
⁷ Faculty of Health/School of Medicine, Witten/Herdecke University, Cologne, Germany.
⁸ HP2 Laboratory, Inserm U1042 Unit, Grenoble Alps University, Grenoble, France.
⁹ EFCR Laboratory, Thorax and Vessels, Grenoble Alps University Hospital, Grenoble, France.

PMID: 30262577
DOI: 10.1183/13993003.011822018

Abstract

Patient-centred outcomes are significantly modified by long-term home noninvasive ventilation (NIV), but a short, self-administered, specific tool for routine clinical assessment is lacking. The aim of this study was to develop and validate the S³-NIV questionnaire, a short questionnaire to measure respiratory symptoms, sleep quality and NIV-related side effects.Patients with stable disease who were under long-term home NIV were recruited from three outpatient NIV services. Questionnaire development consisted of a selection of core items for analysis, followed by item reduction, validation and test-retest reliability.338 patients completed a 22-item questionnaire. 11 items were removed because of non-scalability (n=2), redundancy (n=8) and lack of fit (n=1). The final version of the S³-NIV questionnaire consisted of 11 items covering two dimensions: "respiratory symptoms" (Cronbach's α=0.84) and "sleep & NIV-related side effects" (Cronbach's α=0.77). Convergent validity was high between the "respiratory symptoms" subscale of the S³-NIV questionnaire and the St George's Respiratory Questionnaire (rho= -0.76, p<0.001), and between the "sleep & NIV-related side effects" subscale and the Quebec Sleep Questionnaire (rho=0.51, p<0.001). The S³-NIV questionnaire had good test--retest reliability after 4 weeks (intraclass correlation coefficient=0.72).The S³-NIV questionnaire is a short, valid and repeatable self-completed tool for the routine clinical assessment of patients undergoing home NIV.

Publication types

Multicenter Study
Research Support, Non-U.S. Gov't
Validation Study

MeSH terms

Adult
Aged
Female
France
Health Status
Home Care Services*
Humans
Male
Middle Aged
Noninvasive Ventilation / methods*
Obesity Hypoventilation Syndrome / therapy
Patient Outcome Assessment*
Pulmonary Disease, Chronic Obstructive / therapy
Sleep / physiology
Sleep Apnea Syndromes / therapy
Surveys and Questionnaires*