Enhancing the Detection of Barrett Esophagus

Thorac Surg Clin. 2018 Nov;28(4):453-464. doi: 10.1016/j.thorsurg.2018.07.011.

Abstract

In Western countries, the incidence of esophageal adenocarcinoma has increased rapidly in parallel with its premalignant condition, Barrett esophagus (BE). Unlike colonoscopy, endoscopic screening for BE is not currently recommended for all patients; however, surveillance endoscopy is advocated for patients with established BE. Novel imaging and sampling techniques have been developed and investigated for the purpose of improving the detection of Barrett esophagus, dysplasia, and neoplasia. This article discusses several screening and surveillance techniques, including Seattle protocol, chromoendoscopy, electronic chromoendoscopy, wide area transepithelial sampling with 3-dimensional analysis, nonendoscopic sampling devices, and transnasal endoscopy.

Keywords: Barrett esophagus; Endoscopic imaging; Narrow band imaging; Neoplasia; Transnasal endoscopy; Wide area transepithelial sampling with 3-dimensional analysis.

Publication types

  • Review

MeSH terms

  • Adenocarcinoma / diagnosis*
  • Adenocarcinoma / etiology
  • Barrett Esophagus / diagnosis*
  • Barrett Esophagus / etiology
  • Biopsy
  • Coloring Agents
  • Esophageal Neoplasms / diagnosis*
  • Esophageal Neoplasms / etiology
  • Esophagoscopy / methods
  • Gastroesophageal Reflux / complications
  • Gastroesophageal Reflux / diagnosis*
  • Humans
  • Indicators and Reagents
  • Optical Imaging
  • Precancerous Conditions / diagnosis*

Substances

  • Coloring Agents
  • Indicators and Reagents

Supplementary concepts

  • Adenocarcinoma Of Esophagus