Clostridioides difficile: a potential source of NpmA in the clinical environment

Jane W Marsh; Marissa P Pacey; Chinelo Ezeonwuka; Sara L Ohm; Dan Snyder; Vaughn S Cooper; Lee H Harrison; Yohei Doi; Mustapha M Mustapha

doi:10.1093/jac/dky420

Clostridioides difficile: a potential source of NpmA in the clinical environment

J Antimicrob Chemother. 2019 Feb 1;74(2):521-523. doi: 10.1093/jac/dky420.

Authors

Jane W Marsh^{1

2}, Marissa P Pacey^{1

2

3}, Chinelo Ezeonwuka^{1

2}, Sara L Ohm^{1

2}, Dan Snyder⁴, Vaughn S Cooper⁴, Lee H Harrison^{1

2}, Yohei Doi^{1

3

5}, Mustapha M Mustapha^{1

2

3}

Affiliations

¹ Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
² Microbial Genomic Epidemiology Laboratory (MiGEL), University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
³ Center for Innovative Antimicrobial Therapy, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
⁴ Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
⁵ Department of Microbiology, Fujita Health University, Aichi, Japan.

No abstract available

Publication types

Letter
Research Support, N.I.H., Extramural

MeSH terms

Aminoglycosides / pharmacology
Animals
Anti-Bacterial Agents / pharmacology
Cattle / microbiology
Clostridioides difficile / drug effects
Clostridioides difficile / enzymology
Clostridioides difficile / genetics*
Clostridium Infections / microbiology
Drug Resistance, Multiple, Bacterial / genetics*
Escherichia coli Proteins / genetics
Gene Transfer, Horizontal
Genome, Bacterial*
Humans
Methyltransferases / genetics*
Swine / microbiology

Substances

Aminoglycosides
Anti-Bacterial Agents
Escherichia coli Proteins
Methyltransferases
NpmA protein, E coli

Grants and funding

R01 AI127472/AI/NIAID NIH HHS/United States