Precision Medicine: Role of Proteomics in Changing Clinical Management and Care

J Proteome Res. 2019 Jan 4;18(1):1-6. doi: 10.1021/acs.jproteome.8b00504. Epub 2018 Oct 22.

Abstract

It is now possible to collect large sums of health-related data which has the potential to transform healthcare. Proteomics, with its central position as downstream of genetics and epigenetic inputs and upstream of biochemical outputs and integrators of environmental signals, is well-positioned to contribute to health discoveries and management. We present our perspective on the role of proteomics and other Omics in precision health and medicine.

Keywords: big data; individualized medicine; mass spectrometry; precision medicine; proteomics; remote monitoring.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Aging / physiology
  • Biomarkers / blood
  • Data Collection
  • Delivery of Health Care / trends*
  • Epigenomics
  • Forecasting
  • Humans
  • Machine Learning
  • Phenotype
  • Precision Medicine / economics
  • Precision Medicine / methods*
  • Proteome / analysis
  • Proteomics / methods*
  • Risk Assessment / methods

Substances

  • Biomarkers
  • Proteome