Mixed Palettes of Melanopsin Phototransduction

Cell. 2018 Oct 18;175(3):637-639. doi: 10.1016/j.cell.2018.09.046.

Abstract

Animal photoreceptors divide into two fundamental classes, ciliary and rhabdomeric. Jiang and colleagues demonstrate that this boundary is disregarded by the intrinsically photosensitive retinal ganglion cells of mammals. These neurons draw from phototransduction mechanisms of both classes, enriching the signals that they produce to drive a diversity of visual functions.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Animals
  • Light Signal Transduction
  • Nucleotides
  • Retinal Ganglion Cells*
  • Rod Opsins*

Substances

  • Nucleotides
  • Rod Opsins
  • melanopsin