Management of recurrent pleural mesothelioma: Successful rechallenge with nintedanib in combination with chemotherapy

Clin Case Rep. 2018 Sep 4;6(10):2000-2004. doi: 10.1002/ccr3.1775. eCollection 2018 Oct.

Abstract

Malignant pleural mesothelioma (MPM) is a rare neoplasm, generally caused by asbestos exposure. This case details how a patient treated with nintedanib during the LUME-Meso study was rechallenged with nintedanib. The findings highlight the benefit of nintedanib rechallenge and the potential use of continuous anti-angiogenic therapy in MPM treatment.

Keywords: anti‐angiogenic; disease progression; malignant pleural mesothelioma; nintedanib.

Publication types

  • Case Reports