Reversal of intestinal failure associated liver disease fibrosis in a patient receiving long term home parenteral nutrition

A Bond; S Hayes; A Abraham; A Teubner; K Farrer; L Pironi; S Lal

doi:10.1016/j.clnesp.2018.09.002

Reversal of intestinal failure associated liver disease fibrosis in a patient receiving long term home parenteral nutrition

Clin Nutr ESPEN. 2018 Dec:28:228-231. doi: 10.1016/j.clnesp.2018.09.002. Epub 2018 Sep 27.

Authors

A Bond¹, S Hayes², A Abraham³, A Teubner³, K Farrer³, L Pironi⁴, S Lal³

Affiliations

¹ Intestinal Failure Unit, Salford Royal Foundation Trust, Salford, UK. Electronic address: [email protected].
² Dept of Histopathology, Salford Royal Foundation Trust, Salford, UK.
³ Intestinal Failure Unit, Salford Royal Foundation Trust, Salford, UK.
⁴ Center for Chronic Intestinal Failure, Department of Digestive System, St. Orsola-Malpighi Hospital, University of Bologna, Italy.

PMID: 30390886
DOI: 10.1016/j.clnesp.2018.09.002

Abstract

Intestinal failure associated liver disease (IFALD) is frequent problem encountered when managing patients receiving parenteral nutrition (PN). Its occurrence is often multifactorial and modification of these factors is vital for the management of such hepatic dysfunction. The use of novel lipid preparations can form part of this management strategy. We present a case whereby such modification of contributing factors, including lipid preparations, led to improvements in IFALD and reversal of hepatic fibrosis.

Publication types

Case Reports

MeSH terms

Adult
Humans
Intestinal Pseudo-Obstruction*
Liver Cirrhosis / complications
Liver Cirrhosis / diet therapy*
Malabsorption Syndromes / complications
Malabsorption Syndromes / diet therapy*
Male
Parenteral Nutrition, Home*