Second-trimester Ultrasound and Neuropathologic Findings in Congenital Zika Virus Infection

Pediatr Infect Dis J. 2018 Dec;37(12):1290-1293. doi: 10.1097/INF.0000000000002080.

Abstract

Zika virus is a mosquito-borne virus that causes congenital Zika syndrome, characterized by microcephaly and other fetal brain anomalies. This case report presents a case of Zika virus-related fetal brain anomalies including pathologic evidence of cerebral neuronal apoptosis and macrophage infiltrates and intracerebral calcification, ventriculomegaly and corpus callosum dysgenesis detected by ultrasound at 18 weeks of pregnancy.

Publication types

  • Case Reports
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Brain / diagnostic imaging*
  • Brain / pathology
  • Female
  • Humans
  • Nervous System Diseases / diagnostic imaging
  • Nervous System Diseases / virology*
  • Pregnancy
  • Pregnancy Complications, Infectious / diagnostic imaging
  • Pregnancy Trimester, Second
  • Ultrasonography, Prenatal / methods*
  • Zika Virus
  • Zika Virus Infection / congenital
  • Zika Virus Infection / diagnostic imaging*