Unlocking the Potential for Endogenous Repair to Restore Sight

Rachael A Pearson; Robin R Ali

doi:10.1016/j.neuron.2018.10.035

Unlocking the Potential for Endogenous Repair to Restore Sight

Neuron. 2018 Nov 7;100(3):524-526. doi: 10.1016/j.neuron.2018.10.035.

Authors

Rachael A Pearson¹, Robin R Ali²

Affiliations

¹ University College London Institute of Ophthalmology, 11-43 Bath Street, London EC1V 9EL, UK. Electronic address: [email protected].
² University College London Institute of Ophthalmology, 11-43 Bath Street, London EC1V 9EL, UK; Kellogg Eye Center, University of Michigan, 1000 Wall Street, Ann Arbor, MI 48105, USA.

PMID: 30408440
DOI: 10.1016/j.neuron.2018.10.035

Abstract

The eye often leads the way in the development of novel strategies for treating neurodegenerative disorders. Here, we highlight an exciting new study examining the potential for reactivating endogenous repair mechanisms and enabling the mammalian retina to repair itself.

Publication types

Review

MeSH terms

Animals
Cell Proliferation / genetics
Ependymoglial Cells / physiology
Humans
Photoreceptor Cells / physiology*
Regeneration / genetics
Regeneration / physiology*
Retina / physiology*
Retina / physiopathology
Retinal Degeneration / genetics
Retinal Degeneration / physiopathology*
Retinal Degeneration / therapy
Visual Perception / physiology*

Abstract

Publication types

MeSH terms

Grants and funding