Validation of the Chinese version of the Hamilton Rating Scale for Depression in adults with epilepsy

Epilepsy Behav. 2018 Dec:89:148-152. doi: 10.1016/j.yebeh.2018.10.009. Epub 2018 Nov 8.

Abstract

Objective: This study aimed to validate the Chinese version of the 17-item Hamilton Rating Scale for Depression (C-HRSD-17) for use in adult patients with epilepsy (PWE).

Methods: A consecutive sample of Chinese adult PWE from a tertiary hospital was examined using the C-HRSD-17 and the Mini International Neuropsychiatric Interview (MINI) Plus Chinese Version 5.0.0.

Results: A total of 191 PWE completed the assessment of depression. According to the MINI, thirty patients (15.7%) had current major depressive disorder (MDD). The Cronbach's α coefficient for the C-HRSD-17 was 0.832. Receiver operating characteristic (ROC) analysis showed an area under the curve (AUC) of 0.983 (95% CI = 0.968-0.998). With a cutoff score of 9, the C-HRSD-17 demonstrated the best psychometric properties, with a sensitivity of 96.7%, a specificity of 93.8%, a positive predictive value (PPV) of 74.4%, and a negative predictive value (NPV) of 99.3%.

Conclusion: The C-HRSD-17 proved to be a valid and reliable assessment tool, with a cutoff score of 9 for screening of current MDD in Chinese adult PWE.

Keywords: Depression; Epilepsy; Hamilton Rating Scale for Depression; Validation.

Publication types

  • Research Support, Non-U.S. Gov't
  • Validation Study

MeSH terms

  • Adult
  • Area Under Curve
  • China
  • Depressive Disorder / diagnosis*
  • Epilepsy / psychology*
  • Female
  • Humans
  • Male
  • Mass Screening / methods
  • Middle Aged
  • Psychiatric Status Rating Scales*
  • Psychometrics / instrumentation
  • ROC Curve
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Young Adult