Hyperuricemia-associated Mesoamerican Nephropathy: Case Report and Review of Literature

Adebayo Atanda; Janna Henry; Gbeminiyi Samuel; Olusayo Fadiran; Curtis Frederick; Oluwatosin Omole; Kolapo Idowu; C C Mere

doi:10.7759/cureus.3282

Hyperuricemia-associated Mesoamerican Nephropathy: Case Report and Review of Literature

Cureus. 2018 Sep 11;10(9):e3282. doi: 10.7759/cureus.3282.

Authors

Adebayo Atanda¹, Janna Henry¹, Gbeminiyi Samuel², Olusayo Fadiran³, Curtis Frederick¹, Oluwatosin Omole⁴, Kolapo Idowu⁵, C C Mere⁶

Affiliations

¹ Internal Medicine, Howard University Hospital, Washington, D.C., USA.
² Internal Medicine, Howard University Hospital, Hyattsville, USA.
³ Medicine, Howard University Hospital, Washington, D.C., USA.
⁴ Family Medicine, Howard University Hospital, Washington, D.C., USA.
⁵ Family Medicine, Howard University Hospital, Orlando, USA.
⁶ Nephrology Unit, Howard University Hospital, Washington, D.C., USA.

Abstract

Mesoamerican nephropathy (MeN), formerly called chronic kidney disease of unknown cause (CKDu), refers to chronic kidney disease (CKD) that presents in young and middle-aged Central Americans in the absence of any clear etiology. MeN is a relatively new diagnosis with rapidly rising prevalence in specific regions of El Salvador and Nicaragua, Guatemala, and Costa Rica. It is seldom associated with hyperuricemia. We present a case of a patient with gouty arthritis and hyperuricemia with associated CKD due to MeN. We also provide a review of literature of this disease.

Keywords: aki; ckd; gout; hyperuricemia; mesoamerican nepropathy; nephropathy; uric acid.

Publication types

Case Reports