Evolving to End a Toxic Relationship: ADP Ribosylation in Interbacterial Warfare

Elizabeth A Mueller; Petra Anne Levin

doi:10.1016/j.cell.2018.10.051

Evolving to End a Toxic Relationship: ADP Ribosylation in Interbacterial Warfare

Cell. 2018 Nov 15;175(5):1182-1184. doi: 10.1016/j.cell.2018.10.051.

Authors

Elizabeth A Mueller¹, Petra Anne Levin²

Affiliations

¹ Department of Biology, Washington University in St. Louis, St. Louis, MO 63130, USA.
² Department of Biology, Washington University in St. Louis, St. Louis, MO 63130, USA. Electronic address: [email protected].

Abstract

Long before pathogenic interactions with eukaryotic cells evolved, bacteria were competing with one another for limited resources. In this issue, Ting et al. (2018) identify previously unappreciated players in the interbacterial arms race that may be the evolutionary ancestors of eukaryotic cell-targeting ADP-ribosyltransferase toxins.

Publication types

Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, Non-P.H.S.
Comment

MeSH terms

ADP Ribose Transferases*
ADP-Ribosylation
Adenosine Diphosphate
Bacteria
Toxins, Biological*

Substances

Toxins, Biological
Adenosine Diphosphate
ADP Ribose Transferases

Grants and funding

R35 GM127331/GM/NIGMS NIH HHS/United States