Fecal microbiota transplantation with frozen capsules for a patient with refractory acute gut graft-versus-host disease

Blood Adv. 2018 Nov 27;2(22):3097-3101. doi: 10.1182/bloodadvances.2018024968.

Abstract

  1. Bacterial diversity was restored after FMT with oral frozen capsules, with improvement of diarrhea.

  2. Oral FMT for steroid-refractory acute gGVHD is feasible and could be effective.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Bone Marrow Transplantation / adverse effects
  • Capsules / chemistry
  • Diarrhea / prevention & control
  • Enterococcus / genetics
  • Enterococcus / isolation & purification
  • Fecal Microbiota Transplantation*
  • Feces / microbiology*
  • Female
  • Freezing
  • Glucocorticoids / therapeutic use
  • Graft vs Host Disease / diagnosis*
  • Graft vs Host Disease / drug therapy
  • Graft vs Host Disease / etiology
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy
  • Severity of Illness Index
  • Young Adult

Substances

  • Capsules
  • Glucocorticoids
  • Immunosuppressive Agents