Abstract
Since January 2018, over 53,000 hospitalisations and six deaths due to hand, foot and mouth disease (HFMD) have occurred across Vietnam with most cases from September onward. In a large tertiary referral hospital, Ho Chi Minh City, enterovirus A71 subgenogroup C4 was predominant, while B5 was only sporadically detected. The re-emergence of C4 after causing a severe HFMD outbreak with > 200 deaths in 2011-12 among susceptible young children raises concern of another impending severe outbreak.
Keywords:
Enteroviruses; Vietnam; enterovirus A71; foot and mouth disease; hand.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Child
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Child, Preschool
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Disease Outbreaks*
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Enterovirus A, Human / classification
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Enterovirus A, Human / genetics
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Enterovirus A, Human / isolation & purification*
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Enterovirus Infections / diagnosis
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Enterovirus Infections / epidemiology*
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Epidemics
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Female
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Genome, Viral / genetics*
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Hand, Foot and Mouth Disease / epidemiology*
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Hand, Foot and Mouth Disease / genetics
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Hand, Foot and Mouth Disease / virology*
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Hospitalization / statistics & numerical data*
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Humans
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Infant
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Male
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Sequence Analysis, RNA
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Vietnam / epidemiology