The incidence, indications and predictors of acute pacemaker implantation after ablation of persistent atrial fibrillation

Clin Res Cardiol. 2019 Jun;108(6):651-659. doi: 10.1007/s00392-018-1393-1. Epub 2018 Nov 20.

Abstract

Introduction: Patients with persistent atrial fibrillation (AF) may additionally suffer from a concealed sinus node disease. We sought to determine the incidence, indications and predictors of acute pacemaker [PM] implantation within 1 week after the ablation of persistent AF.

Methods and results: We performed a retrospective analysis of patients, who had had an ablation of persistent AF at our center. Between 01/2011 and 08/2016, 1234 patients (mean age 65 ± 10 years, 66.7% male) without prior PM implantation underwent an ablation of persistent AF. Pulmonary vein isolation (PVI) was performed in 1158 (93.8%), the additional ablation of complex fractionated atrial electrograms (CFAE) in 1109 (89.9%) and linear ablation in 524 (42.5%) patients. Temporary cardiac pacing was necessary in 27 (2.2%) patients. The temporary PM was removed in 15 patients (1.2%) because sinus node recovered after a median of 1.0 (minimum 0.1-maximum 2.0) day. The remaining 12 (1.0%) patients required the implantation of a permanent PM. Another 13 (1.1%) patients required permanent PM implantation without prior temporary pacing. In a multivariable regression model, age [OR 1.07 (1.02-1.12), p = 0.006], sinus pauses prior to ablation [OR 7.97 (2.36-26.88), p = 0.001] and atria with low voltage [OR 2.83 (1.31-6.11), p = 0.008] were identified as significant predictors for acute cardiac pacing.

Conclusion: Acute cardiac pacing within 1 week after the ablation of persistent AF was necessary in 40 (3.2%) patients. Age, sinus pauses in history prior to ablation and the existence of low-voltage areas in the atria were identified as relevant risk factors.

Keywords: Ablation; Acute cardiac pacing; Implantation; Pacemaker; Persistent atrial fibrillation; Sinus arrest; Sinus node disease; Temporary cardiac pacing.

MeSH terms

  • Aged
  • Atrial Fibrillation / diagnosis
  • Atrial Fibrillation / epidemiology
  • Atrial Fibrillation / physiopathology
  • Atrial Fibrillation / surgery*
  • Cardiac Pacing, Artificial*
  • Catheter Ablation* / adverse effects
  • Female
  • Germany / epidemiology
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Pacemaker, Artificial*
  • Retrospective Studies
  • Risk Assessment
  • Risk Factors
  • Sick Sinus Syndrome / diagnosis
  • Sick Sinus Syndrome / epidemiology
  • Sick Sinus Syndrome / physiopathology
  • Sick Sinus Syndrome / therapy*
  • Time Factors
  • Treatment Outcome