Unrecognised cardiovascular disease in type 2 diabetes: is it time to act earlier?

Cardiovasc Diabetol. 2018 Nov 21;17(1):145. doi: 10.1186/s12933-018-0788-7.

Abstract

Cardiovascular disease (CVD) is the most significant prognostic factor in individuals with type 2 diabetes (T2D). However, a significant number of individuals may develop CVD that does not present with the classic angina-related or heart failure symptoms. In these cases, CVD may seem to be 'silent' or 'asymptomatic', but may be more accurately characterised as unrecognised diabetic cardiac impairment. An initial step to raise awareness of unrecognised CVD in individuals with T2D would be to reach a consensus regarding the terminology used to describe this phenomenon. By standardising the terminologies, and agreeing on the implementation of an efficient screening program, it is anticipated that patients will receive an earlier diagnosis and appropriate and timely treatment. Given the availability of anti-diabetic medications that have been shown to concomitantly reduce CV risk and mortality, it is imperative to improve early identification and initiate treatment as soon as possible in order to enable as many patients with T2D as possible to benefit.

Keywords: Asymptomatic; Atypical; Cardiovascular disease; Screening; Silent; Type 2 diabetes; Unrecognised.

MeSH terms

  • Asymptomatic Diseases
  • Biomarkers / blood
  • Blood Glucose / drug effects
  • Blood Glucose / metabolism
  • Cardiovascular Diseases / diagnosis
  • Cardiovascular Diseases / mortality
  • Cardiovascular Diseases / therapy*
  • Diabetes Mellitus, Type 2 / blood
  • Diabetes Mellitus, Type 2 / diagnosis
  • Diabetes Mellitus, Type 2 / drug therapy*
  • Diabetes Mellitus, Type 2 / mortality
  • Early Diagnosis
  • Humans
  • Hypoglycemic Agents / therapeutic use*
  • Mass Screening
  • Predictive Value of Tests
  • Prognosis
  • Risk Assessment
  • Risk Factors

Substances

  • Biomarkers
  • Blood Glucose
  • Hypoglycemic Agents