Vaccination of nonallergic individuals with recombinant hypoallergenic fragments of birch pollen allergen Bet v 1: Safety, effects, and mechanisms

J Allergy Clin Immunol. 2019 Mar;143(3):1258-1261. doi: 10.1016/j.jaci.2018.11.011. Epub 2018 Nov 22.
No abstract available

Publication types

  • Letter
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Allergens / administration & dosage*
  • Allergens / adverse effects
  • Allergens / genetics
  • Allergens / immunology
  • Antigens, Plant / administration & dosage*
  • Antigens, Plant / adverse effects
  • Antigens, Plant / genetics
  • Antigens, Plant / immunology
  • Betula / immunology*
  • Double-Blind Method
  • Female
  • Humans
  • Immunoglobulin E / immunology
  • Immunoglobulin G / immunology
  • Male
  • Pollen / immunology*
  • Recombinant Proteins / administration & dosage
  • Recombinant Proteins / adverse effects
  • Rhinitis, Allergic, Seasonal / prevention & control*
  • Vaccination* / adverse effects
  • Young Adult

Substances

  • Allergens
  • Antigens, Plant
  • Immunoglobulin G
  • Recombinant Proteins
  • Bet v 1 allergen, Betula
  • Immunoglobulin E

Associated data

  • ClinicalTrials.gov/NCT01353924