Patients with "ALPS-like phenotype" diagnosed with immune dysregulation due to LRBA deficiency

Pediatr Blood Cancer. 2019 Mar;66(3):e27558. doi: 10.1002/pbc.27558. Epub 2018 Nov 26.

Authors

Karen S Fernández¹, Reuben Antony², Ashish Kumar³

Affiliations

¹ Valley Children's Health Care, Cancer and Blood Disorders Center, University of California San Francisco-Fresno, Madera, California.
² Department of Pediatric Hematology and Oncology, UC Davis Comprehensive Cancer Center, UC Davis Children's Hospital, Sacramento, California.
³ Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

PMID: 30479033
DOI: 10.1002/pbc.27558

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Abatacept / therapeutic use*
Adaptor Proteins, Signal Transducing / deficiency*
Adaptor Proteins, Signal Transducing / genetics
Autoimmune Lymphoproliferative Syndrome / drug therapy
Autoimmune Lymphoproliferative Syndrome / genetics
Autoimmune Lymphoproliferative Syndrome / immunology*
Child, Preschool
Humans
Immunologic Deficiency Syndromes / drug therapy
Immunologic Deficiency Syndromes / genetics
Immunologic Deficiency Syndromes / immunology*
Immunosuppressive Agents / therapeutic use
Male
Mutation
Prognosis

Substances

Adaptor Proteins, Signal Transducing
Immunosuppressive Agents
Abatacept
LRBA protein, human