Yield and consistency of arrhythmia detection with patch electrocardiographic monitoring: The Multi-Ethnic Study of Atherosclerosis

J Electrocardiol. 2018 Nov-Dec;51(6):997-1002. doi: 10.1016/j.jelectrocard.2018.07.027. Epub 2018 Jul 30.

Abstract

Background: Patch electrocardiographic (ECG) monitors permit extended noninvasive ambulatory monitoring. To guide use of these devices, information is needed about their performance. We sought to determine in a large general population sample the acceptability of patch ECG monitors, the yield of arrhythmia detection, and the consistency of findings in participants monitored twice.

Methods: In the Multi-Ethnic Study of Atherosclerosis, 1122 participants completed one or two monitoring episodes using the Zio Patch XT, a single-channel ECG patch monitor capable of recording for 14 days. Recordings were analyzed for atrial fibrillation (AF), atrial flutter, atrioventricular block, pauses, and supraventricular and ventricular ectopy.

Results: The mean(SD) age at the time of monitoring was 75(8) years, 52% were men, and 15% had a prior history of clinically-recognized AF/flutter. The median monitoring duration was 13.8 days. Among 804 participants with no prior clinical history of AF/flutter and at least 12 days of monitoring on a single device, AF/flutter was detected in 32 (4.0%); in 38% of these, AF/flutter was first detected during days 3 through 12 of monitoring. In participants monitored twice, findings from the two devices showed excellent agreement for supraventricular and ventricular ectopic beats per hour, but only fair agreement for high-grade atrioventricular block and pauses of >3 s duration.

Conclusions: In a general population of older individuals, new diagnoses of AF/flutter were made in 4.0% of participants without a prior history. A single monitoring episode accurately estimated rates of supraventricular and ventricular ectopy.

Keywords: Atrial fibrillation; Atrial flutter; ECG screening; Supraventricular ectopy; Ventricular ectopy.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Atherosclerosis / ethnology
  • Atrial Fibrillation / diagnosis*
  • Atrial Fibrillation / ethnology
  • Atrial Flutter / diagnosis*
  • Atrial Flutter / ethnology
  • Atrioventricular Block / diagnosis*
  • Atrioventricular Block / ethnology
  • Electrocardiography, Ambulatory / instrumentation*
  • Female
  • Humans
  • Male
  • Mass Screening / instrumentation
  • Middle Aged
  • United States
  • Ventricular Premature Complexes / diagnosis*
  • Ventricular Premature Complexes / ethnology