Contemporary practice and short-term outcomes after liver resections in a complete national cohort

Langenbecks Arch Surg. 2019 Feb;404(1):11-19. doi: 10.1007/s00423-018-1737-3. Epub 2018 Dec 5.

Abstract

Background: Improved outcome after liver resections have been reported in several series, but outcomes from national cohorts are scarce. Our aim was to evaluate nationwide practice and short-term outcomes after liver surgery in a universal healthcare system.

Methods: A complete 5-year cohort of all liver resections from the Norwegian Patient Registry (NPR). Short-term outcomes were aggregated length of stay (a-LoS), reoperation and 90-day mortality.

Results: Of 2118 liver resections, 605 (28.6%) were major, median age was 65 years and 1184 (55%) were male. Most common indication was metastatic disease (n = 1554; 73.4%) and primary malignancy (n = 328; 15.3%). Laparoscopy was performed in 513 (33.9%) of minor and 37 (6.1%) of major liver resections and increased over time to 39.1% of minor resections in 2016. Median a-LoS was 12 days for major resections, 8 days for open minor and 3 days for laparoscopic minor resections. Reoperation was reported for 159 (7.4%) and 90-day mortality for 44 (2.1%). Primary malignancy, male gender, elderly patients and major resections were associated with poorer outcome.

Conclusions: In a national cohort, laparoscopy is used for a substantial proportion of minor resections and was associated with reduced a-LoS. Risk factors for reoperation and mortality were male gender, increased age and major resection for primary malignancy.

Keywords: Laparoscopic; Liver resection; National cohort; Short-term outcomes.

MeSH terms

  • Aged
  • Cohort Studies
  • Female
  • Hepatectomy / adverse effects*
  • Hepatectomy / statistics & numerical data
  • Humans
  • Laparoscopy / adverse effects
  • Laparoscopy / statistics & numerical data
  • Length of Stay
  • Liver Neoplasms / mortality
  • Liver Neoplasms / pathology
  • Liver Neoplasms / surgery*
  • Male
  • Middle Aged
  • Norway / epidemiology
  • Postoperative Complications / epidemiology*
  • Reoperation
  • Survival Rate
  • Treatment Outcome