Triskelion channels might bring Star Wars to the global problem of hypertension

Cell Calcium. 2019 Jan:77:77-78. doi: 10.1016/j.ceca.2018.12.005. Epub 2018 Dec 11.

Abstract

In a compelling new report Zeng et al. (Science 2018) suggest that neuronal Piezo1 and Piezo2 channels sense blood pressure in major arteries above the heart [1]. The data challenge previous proposed baroreceptor mechanisms and add to prior knowledge of Piezo1 channels as sensors of blood flow and key players generally in cardiovascular biology.

Publication types

  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Baroreflex*
  • Blood Pressure
  • Calcium
  • Humans
  • Hypertension*
  • Ion Channels

Substances

  • Ion Channels
  • Calcium