Abstract
Avian influenza A(H9N2) virus isolated from a poultry worker in Pakistan in 2015 was closely related to viruses detected in poultry farms. Observed mutations in the hemagglutinin related to receptor-binding affinity and antigenicity could affect cross-reactivity with prepandemic H9N2 vaccine strains.
Keywords:
Pakistan; Surveillance; avian influenza; evolution; influenza; influenza A(H9N2); poultry workers; viruses; zoonoses.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Animals
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Cross Reactions
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Epidemiological Monitoring
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Epitopes
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Farmers
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Hemagglutinin Glycoproteins, Influenza Virus / genetics*
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Humans
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Influenza A Virus, H9N2 Subtype / genetics*
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Influenza A Virus, H9N2 Subtype / immunology
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Influenza A Virus, H9N2 Subtype / isolation & purification
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Influenza Vaccines / immunology*
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Influenza, Human / epidemiology
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Influenza, Human / virology*
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Male
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Mutation
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Pakistan / epidemiology
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Poultry
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Zoonoses
Substances
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Epitopes
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Hemagglutinin Glycoproteins, Influenza Virus
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Influenza Vaccines