Immunity in the Time of Metastases

David Y Oh; Lawrence Fong

doi:10.1016/j.immuni.2018.12.008

Immunity in the Time of Metastases

Immunity. 2018 Dec 18;49(6):1002-1003. doi: 10.1016/j.immuni.2018.12.008.

Authors

David Y Oh¹, Lawrence Fong²

Affiliations

¹ Division of Hematology/Oncology, Department of Medicine, University of California, San Francisco, CA 94143, USA.
² Division of Hematology/Oncology, Department of Medicine, University of California, San Francisco, CA 94143, USA. Electronic address: [email protected].

PMID: 30566878
DOI: 10.1016/j.immuni.2018.12.008

Abstract

Multiplexed interrogation of tumor genomic and immune features in serial patient metastases reported in a recent issue of Cell (Angelova et al., 2018) reveals a pivotal role for immune editing in shaping clonal evolution of metastases.

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MeSH terms

Clonal Evolution*
Genomics
Humans
Immunity*