Inherited missense variants that affect GFI1B function do not necessarily cause bleeding diatheses

Affiliations

• ¹ Department of Laboratory Medicine, Laboratory of Hematology, Radboudumc, Radboud Institute for Molecular Life Sciences (RIMLS), Nijmegen, the Netherlands.
• ² Department of Cardiovascular Sciences, Center for Molecular and Vascular Biology, University of Leuven, Belgium.
• ³ Centre for Haematology, Hammersmith Campus, Imperial College Academic Health Sciences Centre, Imperial College London, UK.
• ⁴ Imperial College Healthcare NHS Trust, London, UK.
• ⁵ School of Cellular and Molecular Medicine, University of Bristol, UK.
• ⁶ Service d'Hematologie Biologique, Assistance-Publique Hôpitaux de Paris, Centre de Référence des Pathologies Plaquettaires, Hôpital Armand Trousseau, Paris, France.
• ⁷ School of Biomedical Sciences, University of Western Australia, Crawley, Western Australia, Australia.
• ⁸ PathWest Laboratory Medicine, Nedlands, Western Australia, Australia.
• ⁹ Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, UK.
• ¹⁰ National Health Service Blood and Transplant (NHSBT), Cambridge Biomedical Campus, UK.
• ¹¹ NIHR BioResource, Cambridge University Hospitals, Cambridge Biomedical Campus, UK.
• ¹² Medical Research Council Biostatistics Unit, University of Cambridge, Forvie Site, Cambridge Biomedical Campus, UK.
• ¹³ Department of Human Genetics, The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.
• ¹⁴ Strangeways Research Laboratory, The National Institute for Health Research (NIHR) Blood and Transplant Unit in Donor Health and Genomics at the University of Cambridge, UK.
• ¹⁵ BHF Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Cambridge Biomedical Campus, UK.
• ¹⁶ Department of Laboratory Medicine, Laboratory of Hematology, Radboudumc, Radboud Institute for Molecular Life Sciences (RIMLS), Nijmegen, the Netherlands [email protected].