Adalimumab in Psoriasis: How Much Is Enough?

J Invest Dermatol. 2019 Jan;139(1):19-22. doi: 10.1016/j.jid.2018.08.012.

Abstract

Biologic therapies targeting tumor necrosis factor have revolutionized treatment of immune-mediated inflammatory diseases such as psoriasis, but optimal dosing and appropriate use of therapeutic drug monitoring are not yet fully understood. Wilkinson et al. explore these questions in a real-world psoriasis cohort on adalimumab monotherapy, defining a therapeutic range and finding value in early measurement for predicting clinical response.

Publication types

  • Comment

MeSH terms

  • Adalimumab
  • Antibodies, Monoclonal*
  • Antibodies, Monoclonal, Humanized
  • Cohort Studies
  • Etanercept
  • Humans
  • Prospective Studies
  • Psoriasis*
  • Tumor Necrosis Factor-alpha

Substances

  • Antibodies, Monoclonal
  • Antibodies, Monoclonal, Humanized
  • Tumor Necrosis Factor-alpha
  • Adalimumab
  • Etanercept