This study examined predictors of employment service referral and employment outcomes among individuals experiencing chronic homelessness participating in a comprehensive service program emphasizing housing placement and economic independence. The sample included all participants enrolled in the program. Participants self-determined whether to be referred for employment services. Outcomes included (a) whether participants were referred for employment services offered by the program (N = 275); and (b) whether employment was attained among the subsample of participants referred for employment services (N = 135). Logistic regression analyses for the 2 outcomes were conducted. Predictors included demographics and health indicators collected via self-report during program intake. Participants who were younger and racial/ethnic minorities were more likely to seek referrals than those who were older and White/European American. Individuals who were unemployed due to disability were less likely to seek referrals than those who were unemployed but seeking employment. Participants with better reported health and who were unemployed but seeking employment were more likely to attain employment than those with poor health or were unemployed for another reason (e.g., retired, disabled). Findings from this study have implications for employment services implemented in the context of homeless service programs. Future developments in employment services for people who are chronically homeless should include an array of employment services varying in intensity based on need. Other issues to be addressed to facilitate employment and its impact include addressing stigma and increasing earning potential. (PsycINFO Database Record (c) 2019 APA, all rights reserved).