Microwave ablation of osteoid osteoma: initial experience and efficacy

Pediatr Radiol. 2019 Apr;49(4):566-570. doi: 10.1007/s00247-018-4327-1. Epub 2019 Jan 7.

Abstract

Background: Image-guided percutaneous microwave ablation has been used to treat adult osteoid osteomas but has not been thoroughly evaluated in the pediatric population.

Objective: To evaluate the technical feasibility and clinical efficacy of microwave ablation to treat osteoid osteomas in pediatric patients.

Materials and methods: The electronic medical record and imaging archive were reviewed for 24 consecutive patients who had undergone microwave ablation of osteoid osteomas between January 1, 2015, and May 31, 2018, at a single tertiary care pediatric hospital. All patients were diagnosed by clinical and imaging criteria, and referred by a pediatric orthopedic surgeon after failing conservative management with pain medication. The average age of the patients was 13.3 years (range: 3-18 years), and the average size of the osteoid osteoma nidus was 8.8 mm (range: 5-22 mm). Technical success was defined as placement of the microwave antenna at the distal margin of the lesion nidus and achievement of the target ablation temperature. Clinical findings were assessed pre- and post-ablation and clinical success was defined as complete relief of pain without pain medication at 1-month follow-up. The number and severity of complications were also documented.

Results: Clinical success was achieved in 100% of patients (24/24), with all reporting complete cessation of pain medication use 1 week after treatment and 0/10 pain at 1 month. There were 4 minor complications (17%) including access site numbness and a minor soft-tissue infection. There were no major complications.

Conclusion: Microwave ablation is a technically feasible and clinically effective treatment for pediatric osteoid osteomas.

Keywords: Bone; Children; Interventional radiology; Microwave ablation; Osteoid osteoma.

MeSH terms

  • Adolescent
  • Bone Neoplasms / surgery*
  • Catheter Ablation / methods*
  • Child
  • Child, Preschool
  • Cone-Beam Computed Tomography
  • Female
  • Humans
  • Male
  • Microwaves / therapeutic use*
  • Osteoma, Osteoid / surgery*
  • Radiography, Interventional / methods*
  • Retrospective Studies