Ratiometric temperature sensing with fluorescent thermochromic switches

Chem Commun (Camb). 2019 Jan 25;55(8):1112-1115. doi: 10.1039/c8cc09482a. Epub 2019 Jan 9.

Abstract

The connection of fluorescent chromophores to switchable heterocycles translates into molecular probes with ratiometric response to temperature. The opening and closing of their heterocyclic component equilibrates two emissive species with resolved fluorescence. Their relative emission intensities change monotonically with temperature to enable the visualization of thermal distributions at the microscale.